According to OK!, Sam is accused of grinding up Risperdal and Seroquel in order to drug Britney. Both drugs are antipsychotic medications, one for bi-polar and the other for schizophrenia.

These are not the usual slip your boss a mickey type of drugs. These are for mental disorders. They also have some crappy side effects from a "disfiguring" disease to "thoughts about suicide".

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Risperdal (risperidone), released in 1994, is one of the atypical antipsychotic medications used to treat schizophrenia and psychotic disorders. The drug helps manage schizophrenia's positive symptoms (e.g., visual and auditory hallucinations, delusions, and thought disturbances) and may also help treat the illness’ negative symptoms (e.g., social withdrawal, apathy, lack of motivation, and inability to experience pleasure). It may also be useful in treating acute mania and severe depression in combination with antidepressant medications.

When taken at the manufacturer's recommended dose of 6 mg/day or less. Risperdal has been observed to cause no higher rate of significant side effects than the rate observed with placebo. These side effects include extrapyramidal symptoms (muscle stiffness, tremors, and body shakes).

More significant possible side effects, affecting some patients but not all, include low blood pressure; dizziness, especially when standing up suddenly; heart palpitations; sleepiness; constipation; weight gain; sexual dysfunction; and fatigue.

Tardive dyskinesia (TD), a disfiguring side effect that occurs in some patients taking antipsychotic drugs, may not be a major risk associated with Risperdal use, although it may take years before researchers can fully assess the risk.

Risperdal can be taken before, during, or after meals. Patients should be cautious about operating hazardous machinery, including driving, until they are certain they are not adversely affected.

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Seroquel is an antipsychotic medication. It works by changing the actions of chemicals in the brain. Seroquel is used to treat the symptoms of psychotic conditions such as schizophrenia and bipolar disorder (manic depression).

Seroquel is not for use in psychotic conditions that are related to dementia. Seroquel has caused fatal pneumonia or heart failure in older adults with dementia-related conditions. Stop using Seroquel and call your doctor at once if you have the following symptoms: fever, stiff muscles, confusion, sweating, fast or uneven heartbeats, uncontrolled muscle movements, symptoms that come on suddenly such as numbness or weakness, severe headache, and problems with vision, speech, or balance.

You may have thoughts about suicide when you first start taking an antidepressant, especially if you are younger than 24 years old.